Precision Health
A: Blood test attempts to provide a specific answer to whether one has a medical condition or not. Genetic testing is to find out each individual’s inherited predisposition for disease including cancer which is controlled by the individual’s gene composition. This knowledge would allow one to manage his/her wellbeing preventing occurrence of serious sickness, thus achieving a healthy lifestyle and growing old gracefully.
A: Genetic predisposition to a particular illness can be modified by gene expression or environmental factors in late life. Hence, the illness may not develop or may be mild. The main goal from the genetic testing is to know one’s own physical and/or mental weakness so that they can be monitored, supported or prevented with well organised planning and medical supervision.
A: In practice, genome information can be used to direct modern technology, nutritional support and life style change (e.g. stop smoking) to reduce chance of or preventing germline illness. It also increases one’s health awareness so that regular medical monitoring or screening would ensure early detection & effective treatment of disease/cancer (e.g. regular mammogram for breast cancer, Pap smear for cervical cancer, HPV vaccine for preventing cancer of the cervix etc). Paediatric genetic testing also gives information on the child’s personality, talent, physique and inherent potential. One can use this information to guide or plan the children’s academic or intellectual development to ensure a successful future.
A: A gene is made up of DNA which directs cellular growth and/or function, thus governs the body & mental composition unique to that individual (for example, height, hair colour or IQ) that can be passed onto the next generation. It also regulates biochemical processes that give rises to and control of specific body function including immunity. At molecular level, the biological and chemical process that supports life relies on protein to carry out. Protein structures and functions vary greatly but their building blocks consist only of amino acid. Gene works by controlling the sequence and combination of the amino acids which in turns codes the action and effect of that particular protein for particular cellular process or manifestation. The DNA sequence is specific to that individual and is transmitted to the offspring via chromosomes. A chromosome consists of a long strand of DNA containing many genes. There are 46 chromosomes (in 23 pairs) in human; one comes from the mother and the other from the father.
A: Cancer is formed due to alternation of the cell’s normal DNA which allows it to escape detection and destruction by the normal immune system. In-born DNA error indicates that the person with such mutation has the potential for such tumour formation but not an absolute development. What that test also does not predict is the timing of such tumour transformation or its aggressiveness.
When tumour is formed, it produces tumour protein antigen or DNA fragments after cell death. The detection of these tumour biomarkers is the basis of cancer genetic testing. The knowledge of these tumour DNA mutations helps to select therapy based on the tumour DNA characteristics, treatment monitoring and follow up. Alternatively, one can boost one’s immune system to kill off these mutant cells early on to prevent cancer formation. This is the essence of personalised medicine/treatment that is being carried out in our centre.
A: All test results performed in our centre can be collected in person or authorized person. (The authorized person must obtain a letter of authorization and a copy of the patient’s ID card). As for examinations ordered by your referral doctors, you should collect these reports at your doctor's office.

